A Bioinformatic Analysis of FOXO3 and TGFB3 Variants: Possible Pathways to Survivin Expression

Authors

Elaine Vanterpool, Oakwood University
Jordon Vanterpool, Oakwood University

Faculty Mentor

Dr. Elaine Vanterpool

Files

Description

Cancer affects millions of people worldwide. Recent studies show that survivin, a survival factor, is expressed in cancer cells and can be secreted. In this study, we focused on pathways leading to survivin abnormal expression in cancer cells. We used a bioinformatic approach to analyzing variants that could be associated with regulating survivin expression. The hypothesis of this study is that there are critical mutations of survivin and/or regulators of survivin which may lead to the increased expression of the survivin protein in cancer cells.

Publication Date

2025

City

Huntsville

Disciplines

Biology

Recommended Citation

Vanterpool, Elaine and Vanterpool, Jordon, "A Bioinformatic Analysis of FOXO3 and TGFB3 Variants: Possible Pathways to Survivin Expression" (2025). Student Posters. 113.
https://ouscholars.oakwood.edu/student-posters/113