Faculty Mentor

Dr. Elaine Vanterpool

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Description

Pseudomonas aeruginosa is an opportunistic pathogen that poses significant challenges in clinical treatment due to its production of collagenase. This bacterium can cause several infections including pneumonia, meningitis, septicemia, and a host of other diseases. Collagenase acts as a key virulence factor by breaking down collagen in the host’s extracellular matrix, allowing bacteria to invade tissues. This study hypothesized that the effects of cell secreted collagenase would be inhibited by metronidazole, vanillin, and silver nanoparticles to reduce the pathogenicity of Ps. aeruginosa related infections.

Publication Date

2025

City

Huntsville

Disciplines

Biology

Analyzing the Inhibition Of Chemical Compounds On Collagenase in P. aeruginosa

Included in

Biology Commons

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