Faculty Mentor

Dr. Elaine Vanterpool

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Description

Hypothyroidism is a chronic disease that lacks the production of thyroid hormones. If this disease is not treated with the proper care, it can lead to some serious health effects, or even become fatal. In hypothyroidism levels of thyroid hormones are low. The thyroid gland is a very pivotal part of the endocrine system located at the front of The protein encoded by this gene is the nuclear hormone receptor triiodothyronine. The consequences of untreated or inadequately treated hypothyroidism include infertility, cardiovascular disease, and neurological and musculoskeletal symptoms. Environmental iodine deficiency is the most common cause of thyroid disorders, including hypothyroidism, worldwide, while in areas of iodine sufficiency, the most common cause of primary hypothyroidism is autoimmune thyroiditis (Hashimoto’s disease). It is one of the several receptors for thyroid hormone and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having a certain extent of redundancy, may mediate different thyroid hormone functions.

Publication Date

4-1-2025

City

Huntsville

Disciplines

Biology

Comments

Anaiah Mills, Student Researcher

The Analysis of THRA Variants in Hypothyroidism

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Biology Commons

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