Faculty Mentor

Dr. Elaine Vanterpool

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Description

blood pressure in the body is too high. A medical condition that is well known to be one of the major causes of premature deaths worldwide. Affecting an estimation of 1.28 billion adults . ABCA3 is a protein that is involved in the development of hypertension. ABCA3 is part of the ATP-binding cassette transporter family. It is a multi-membrane spanning protein meaning it has to do with the transporting, signaling and structure of cells. It plays a crucial role in the regulation of pulmonary surfactant homeostasis, but its main objective is to provide instruction to make protein that is involved in the production of surfactant. Surfactant is mixture of phospholipids and proteins that function to reduce surface tension in the lungs. It lines the lung tissue and makes breathing easier. Without it, the tissue surrounding the air sacs will stick together causing a collapsion of the alveoli. Eventually breathing becomes harder and oxygen is not able to make its way in the body.

Publication Date

4-1-2025

City

Huntsville

Disciplines

Biology

Comments

Lisa-Faith Dieujuste, Student Researcher

An Analysis of ABCA3 variants Associated With Hypertension

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Biology Commons

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