An Analysis of DAGLA Variants Associated with ADHD

Authors

Elaine Vanterpool, Oakwood University
Zahra Dulan, Oakwood University

Faculty Mentor

Dr. Elaine Vanterpool

Files

Description

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by impulsivity, difficulty focusing and staying on task, hyperactivity, including restlessness and excessive talking, and deficits in working memory. Individuals with ADHD may also struggle to maintain relationships, regulate emotions, and stay organized. The DAGLA gene has been associated with the ADHD phenotype and is primarily located in brain tissues. It is responsible for encoding diacylglycerol lipase alpha, an enzyme involved in the biosynthesis of key endocannabinoid 2-arachidonoyl glycerol (2-AG). This protein has been shown to play a major role in central nervous system development and synaptic elasticity. This study serves to identify variants of the DAGLA gene associated with ADHD and determine their pathogenicity.

Publication Date

2025

City

Huntsville

Disciplines

Biology

Recommended Citation

Vanterpool, Elaine and Dulan, Zahra, "An Analysis of DAGLA Variants Associated with ADHD" (2025). Student Posters. 68.
https://ouscholars.oakwood.edu/student-posters/68