An Examination of LACC1 variants Linked to Rheumatoid Arthritis

Authors

Elaine Vanterpool, Oakwood University
Rochelle Gunter, Oakwood University

Faculty Mentor

Dr. Elaine Vanterpool

Files

Description

Rheumatoid arthritis is an inflammatory disease with an annual diagnosis rate of 70 cases per 100,000 people. This is a disease that is usually identified by the abnormal entry of immune cells, such as B lymphocytes, T lymphocytes, and innate lymphoid cells, into the synovial tissues of the joints. When these immune cells infiltrate the joints, they can become too active, thereby contributing to the chronic inflammatory response characteristic of the disease. The objective of this study is to identify and evaluate the pathogenic potential of LACC1 variants implicated in the pathogenesis of arthritis. Simple ClinVar identified LACC1 as a gene implicated in the pathogenesis of arthritis, along with its two distinct variants: Cys284Arg and Met1Ile.

Publication Date

2025

City

Huntsville

Disciplines

Biology

Recommended Citation

Vanterpool, Elaine and Gunter, Rochelle, "An Examination of LACC1 variants Linked to Rheumatoid Arthritis" (2025). Student Posters. 92.
https://ouscholars.oakwood.edu/student-posters/92