Faculty Mentor

Dr. Elaine Vanterpool

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Description

The androgen receptor (AR) is a steroid-hormone activated transcription factor that regulates gene expression in response to testosterone and dihydrotestosterone (DHT). While AR has been extensively studied in prostate cancer, emerging research suggests its role in breast cancer, particularly in estrogen receptor-positive (ER-positive) and triple-negative breast cancer (TNBC). This study investigates AR variants associated with breast cancer, assessing their pathogenicity and potential impact on prognosis and treatment.

Publication Date

2025

City

Huntsville

Disciplines

Biology

An Analysis of Androgen Receptor (AR) Variants  in Breast Cancer

Included in

Biology Commons

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