An Analysis of LAMB3 Variants Associated with Amelogenesis Imperfecta

Authors

Elaine Vanterpool, Oakwood University
Aaliyah Ruddock, Oakwood University

Faculty Mentor

Dr. Elaine Vanterpool

Files

Description

Amelogenesis Imperfecta (AI) is an inherited tooth development disorder occurring in both child and adult patients. The teeth of those with this disease are often discolored, quite small, and prone to breakage. Not only can this disease affect the teeth directly but that of the surrounding gum, tissues, ligaments, and alveolar bones. Research has found over 14 different forms of this disease each distinguished by inheritance patterns and the various abnormalities. AI can be inherited through an X linked recessive pattern. This results in the disease being more pronounced in males as females can better combat the disease with their duo-X chromosomes. The significance of this study is to conduct research and analyze the pathogenicity of the LAMB3 gene associated with AI.

Publication Date

2025

City

Huntsville

Disciplines

Biology

Recommended Citation

Vanterpool, Elaine and Ruddock, Aaliyah, "An Analysis of LAMB3 Variants Associated with Amelogenesis Imperfecta" (2025). Student Posters. 79.
https://ouscholars.oakwood.edu/student-posters/79