Impact of SMAD 4 Gene to Juvenile Polyposis Syndrome
Description
Juvenile polyposis syndrome (JPS) is a rare autosomal dominant disease in the gastrointestinal (GI) tract that grows benign, juvenile polyps. With the ability to become malignant in the future, juvenile polyps are a serious threat to children under 18 years old. Once these genes have mutated, this genetic disability will persist within the family for generations. The study aims to understand the impact of mutations within this disease and identify potential pathogenic missense mutations of the SMAD 4 gene found in JPS.
This paper has been withdrawn.