Silver Nanoparticles and Vanillin Can Inhibit Collagenase Activities of Serratia marcescens

Authors

• Elaine Vanterpool, Oakwood UniversityFollow
• Mya St. Louis, Oakwood University
• Josel Bryant, Oakwood University
• Kennedi Ewan, Oakwood University
• Taylor Hall, Oakwood University
• Leah Marcelle, Oakwood University
• Mayah Seal, Oakwood University

Faculty Mentor

Dr. Elaine Vanterpool

Files

Description

Serratia marcescens is a gram-negative, disease-causing agent that belongs to the Enterobacteriaceae family. This rod-shaped microbe causes many infectious diseases such as urinary and respiratory infections, wound infections, and peritonitis, which can result in fatal bacteremia. Collagenase is an enzyme that breaks down collagen, while also playing a key role in the extracellular matrix. Collagenase uses zinc to operate that helps it break down the peptide bonds in collagen. Testing Agents ❖ Metronidazole is an antimicrobial drug used to treat infections caused by different anaerobic bacteria, such as infections in the blood, liver, bones, joints, and meninges. ❖ Vanillin is a compound with promising thrapeutic properties that include anticancer effects, while also regulating gene expression by ist arouma of vanilla. ❖ Silver nanoparticles are nanomaterials/nanoparticles that play a major role in nanotechnology along with nanoscience, and are used in many different medical applications and technologies.

Publication Date

4-1-2025

City

Huntsville

Disciplines

Biology

Comments

Student Researchers: St. Louis, Bryant, Ewan, Hall, Marcelle, Seal.

Recommended Citation

Vanterpool, Elaine; St. Louis, Mya; Bryant, Josel; Ewan, Kennedi; Hall, Taylor; Marcelle, Leah; and Seal, Mayah, "Silver Nanoparticles and Vanillin Can Inhibit Collagenase Activities of Serratia marcescens" (2025). Student Posters. 179.
https://ouscholars.oakwood.edu/student-posters/179