Analysis of Alzheimer's Associated ADAM10 Mutations

Authors

Elaine Vanterpool, Oakwood University
Addie McIver, Oakwood University

Faculty Mentor

Dr. Elaine Vanterpool

Files

Description

Alzheimer’s Disease (AD) is the most common form of Dementia, affecting 10% of people over age 65 as the fifth-leading cause of death. In AD, protein buildup causes amyloid plaques and neurofibrillary tangles in the brain. These tangles can lead to a loss of neuron connection and damage, initially occurring in the hippocampus and entorhinal cortex, which are essential in memory formation. Certain gene mutations associated with an increased risk of AD affect the breakdown and function of proteins that influence processing and cell-signaling. The purpose of this study is to investigate the pathogenicity of AD associated genetic variants of ADAM10.

Publication Date

2025

City

Huntsville

Disciplines

Biology

Recommended Citation

Vanterpool, Elaine and McIver, Addie, "Analysis of Alzheimer's Associated ADAM10 Mutations" (2025). Student Posters. 55.
https://ouscholars.oakwood.edu/student-posters/55